All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis[1].
Molekulargewicht:
284.44
Reinheit:
99.76
CAS Nummer:
[116-31-4]
Formel:
C20H28O
Target-Kategorie:
Apoptosis,Endogenous Metabolite
Anwendungsbeschreibung:
Natural Products
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