Recombinant protein corresponding to aa24-265 from partial human EPCAM, fused to GST-Tag.
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Sequence: QEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVIC SKLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLY DPDCDESGLFKAKQCNGTSTCWCVNTAGVRRTDKDT EITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEIT TRYQLDPKFITSILYENNVITIDLVQNSSQKTQNDVDIAD VAYYFEKDVKGESLFHSKKMDLTVNGEQLDLDPGQTL IYYVDEKAPEFSMQGLK Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.