Inosine Monophosphate Dehydrogenase 2 (Inosine-5-monophosphate Dehydrogenase 2, IMP Dehydrogenase 2, IMPDH 2, IMPDH2, IMPD 2, IMPD2, IMPDH-II), Rabbit
Artikelnummer:
USB-I7654-95D
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| Artikelname: | Inosine Monophosphate Dehydrogenase 2 (Inosine-5-monophosphate Dehydrogenase 2, IMP Dehydrogenase 2, IMPDH 2, IMPDH2, IMPD 2, IMPD2, IMPDH-II), Rabbit |
| Artikelnummer: | USB-I7654-95D |
| Hersteller Artikelnummer: | I7654-95D |
| Alternativnummer: | USB-I7654-95D-200 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Immunogen: | Synthetic peptide selected from the Center region of human IMPDH2 (KLH). |
| IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The protein catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5-monophosphate. Its gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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