Anti-Botulinum neurotoxin type A [CR1], Human IgG1, Fc Silent(TM), kappa, Monoclonal
Artikelnummer:
ABA-AB00803-10.3-BT
Hersteller Artikelnummer:
Ab00803-10.3-BT
Alternativnummer:
ABA-AB00803-10.3-BT
Hersteller:
Absolute Antibody
Wirt:
Human
Kategorie:
Antikörper
Applikation:
FC, NeA
Spezies Reaktivität:
Clostridium
Alternative Synonym:
BoNT/A, BoNT, Botulinum neurotoxin, Bontoxilysin-A, Bontoxilysin A, BOTOX
CR1 was produced by a yeast gene diversity library used to increase the affinitiy of scFv AR2 for BoNT/A2, while maintinaing high affinity binding to BoNT/A2. AR2 was generated after multiple rounds of affinity maturation of the humanized C25, which itself was created by CDR-grafting from the parental murine C25. Murine C25 was prepared by constructing a scFv phage display library from mice immunized with recombinant BoNT/A binding domain (Hc).
