Anti-Kell [MIMA-8], Human IgG1, Fc Silent(TM), kappa, Monoclonal
Artikelnummer:
ABA-AB00916-10.3-BT
Hersteller Artikelnummer:
Ab00916-10.3-BT
Alternativnummer:
ABA-AB00916-10.3-BT
Hersteller:
Absolute Antibody
Wirt:
Human
Kategorie:
Antikörper
Applikation:
FC
Spezies Reaktivität:
Human
Alternative Synonym:
CD238, Kell protein, Kell blood group glycoprotein homolog, Cluster of Differentiation 238
Murine antibodies were produced by immunising BALB/c mice with the mouse erythroleukaemic (MEL) cell line stably expressing high levels of wildtype, full-length human Kell protein. This overexpression allowed several epitopes of Kell protein to serve as the immunogen, resulting in identification of several anti-Kell mAbs with different specificities, of which MIMA-8 targeted the Jsb antigen. Splenocytes were obtained from immunised mice and fused with the P3X63Ag8.653 myeloma cell line to produce a hybridoma.