CD221, IGF1 receptor, Insulin-like growth factor 1 receptor, type I IGF receptor, Insulin-like growth factor I receptor, IGF-I receptor
The original antibody was generated from BALB/c mice hyperimmunized with human IGF-IR extracellular domain (amino acids 1-902) in Ribi adjuvant. Later on the humanized version was created by grafting the hypervariable regions onto human framework regions.