Anti-CD72 [004 (pgG102-004C01)], Human IgG1, kappa, Clone: [004 pgG102-004C01], Monoclonal
Artikelnummer:
ABA-AB04012-10.0
Hersteller Artikelnummer:
Ab04012-10.0
Alternativnummer:
ABA-AB04012-10.0
Hersteller:
Absolute Antibody
Wirt:
Human
Kategorie:
Antikörper
Applikation:
FC
Spezies Reaktivität:
Human
Alternative Synonym:
Lyb-2, B-cell differentiation antigen CD72
The original antibody was isolated from a human scFv phage display library by panning against human CD72 receptor using human tonsillar mononuclear cells. The phage library was further enriched using peripheral blood B lymphocytes as target in presence of anti-CD19 antibody. The final round of panning was done against peripheral blood CD19+B cells and subsequently tested for binding to CD72- transfected L929 cells. Later on the scFv antibody was converted to human IgG1 format using antibody engineering.