[KO Validated] CDK9 Rabbit mAb, Unconjugated

Artikelnummer: ABB-A11145
Artikelname: [KO Validated] CDK9 Rabbit mAb, Unconjugated
Artikelnummer: ABB-A11145
Hersteller Artikelnummer: A11145
Alternativnummer: ABB-A11145-20UL,ABB-A11145-100UL,ABB-A11145-1000UL,ABB-A11145-500UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IF, IHC-P, IP, WB
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: TAK, C-2k, CTK1, CDC2L4, PITALRE, K9
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Klonalität: Monoclonal
Klon-Bezeichnung: [ARC0527]
Molekulargewicht: 43kDa
NCBI: 1025
UniProt: P50750
Reinheit: Affinity purification
Sequenz: RKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNPATTNQTEFERVF
Target-Kategorie: CDK9
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:500 - 1:3000|IHC-P,1:200 - 1:2000|IF/ICC,1:50 - 1:400|IP,0.5µg-4µg antibody for 200µg-400µg extracts of whole cells|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Protein phosphorylation,Signal Transduction,Kinase,Serine threonine kinases,Cell Biology Developmental Biology,Cell Cycle,Immunology Inflammation