Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation:
ABflo 647
Alternative Synonym:
Hdj1, Sis1, HSPF1, Hsp40, RSPH16B
This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the J-domain and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants.
Cross-Reactivity: Human. ResearchArea: Signal Transduction. Shipping: Ice Bag
Flow cytometry: 1X10 6 293T-DNAJB1/HSP40-shRNA-1 cells (pink line),293T-DNAJB1/HSP40-shRNA-2 cells (green line) and 293T-scramble cells (orange line) were intracellularly-stained with ABflo 647 Rabbit anti-Human DNAJB1/HSP40 mAb (A25528,5 µl/Test) or ABflo 647 Rabbit IgG isotype control (A22070,5 µl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line).
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