ABflo 594 Rabbit anti-Human Syk mAb, Monoclonal

Artikelnummer: ABB-A25740
Artikelname: ABflo 594 Rabbit anti-Human Syk mAb, Monoclonal
Artikelnummer: ABB-A25740
Hersteller Artikelnummer: A25740
Alternativnummer: ABB-A25740-5X100T,ABB-A25740-2X100T,ABB-A25740-100T
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: ABflo 594
Alternative Synonym: IMD82, p72-Syk
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Klonalität: Monoclonal
Konzentration: FC (intra)
Molekulargewicht: 72kDa/70kDa
NCBI: 6850
UniProt: P43405
Reinheit: Affinity purification
Target-Kategorie: SYK
Application Verdünnung: FC (intra),5 µl per 10 6 cells in 100 µl volume
Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Protein phosphorylation,Signal Transduction,Kinase,Tyrosine kinases,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood. Shipping: Ice Bag
Flow cytometry: 1X10 6 Human PBMC were surface-stained with APC anti-human CD19 Antibody (5 µl/Test) followed by intracellular staining with ABflo 594 Rabbit anti-Human Syk mAb (A25740,5 µl/Test,left) or ABflo 594 Rabbit IgG isotype control (A23821,5 µl/Test,right).