Chemical compounds corresponding to 4-Hydroxynonenal.
Konjugation:
PE
Alternative Synonym:
4-HNE
4-hydroxy-2-nonenal (4-hydroxynonenal, 4-HNE) is a highly reactive aldehyde generated by the exposure of polyunsaturated fatty acids to peroxides and reactive oxygen species (ROS). It non-enzymatically forms stable protein adducts with histidine, lysine, and cysteine side chains that have been used as biomarkers for oxidative damage in cells. Conditions where 4-HNE immunoreactivity has been observed include include inflammation, neurodegenerative diseases, and ischemic damage to the heart and brain.
Konzentration:
FC (intra)
Reinheit:
Affinity purification
Target-Kategorie:
4-HNE
Application Verdünnung:
FC (intra),5 µl per 10 6 cells in 100 µl volume
Anwendungsbeschreibung:
Cross-Reactivity: Species independent. ResearchArea: Cell Biology,Oxidative Stress. Shipping: Ice Bag
Flow cytometry: 1X10 6 HeLa cells (treated with 4-Hydroxynonenal) were intracellularly-stained with PE Rabbit IgG isotype control (A24172,5 µl/Test,left) or PE Rabbit anti-4-Hydroxynonenal mAb (A26084,5 µl/Test,right).
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