PE/Cyanine5 Mouse anti-Human CD3 mAb, PE/Cy5, Monoclonal

Produktübersicht

• Artikelname: PE/Cyanine5 Mouse anti-Human CD3 mAb, PE/Cy5, Monoclonal
• Artikelnummer: ABB-A26827
• Hersteller Artikelnummer: A26827
• Alternativnummer: ABB-A26827-100T,ABB-A26827-2X100T,ABB-A26827-5X100T
• Hersteller: ABclonal
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: PE/Cy5
• Alternative Synonym: T3E, TCRE, IMD18, CD3epsilon

Produktbeschreibung

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: FC
• Molekulargewicht: 23kDa
• NCBI: 916
• UniProt: P07766
• Reinheit: Affinity purification
• Target-Kategorie: CD3E

Anwendungsbeschreibung

• Application Verdünnung: FC, 5 µl per 10 6 cells in 100 µl volume
• Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Cell Biology Developmental Biology,Apoptosis,Immunology Inflammation,CDs,T Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors. Shipping: Ice Bag

Bilder

Flow cytometry: 1X10 6 Human PBMC were surface-stained with PE/Cyanine5 Mouse IgG2a isotype control (5 µl/Test,left) or PE/Cyanine5 Mouse anti-Human CD3 mAb (A26827,5 µl/Test,right). Cells in the lymphocyte gate were used for analysis.