Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation:
PE
Alternative Synonym:
CPT1, CPT1-L, L-CPT1
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cross-Reactivity: Human. ResearchArea: Cancer,Signal Transduction,Endocrine Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Obesity,Cardiovascular,Lipids,Fatty Acids. Shipping: Ice Bag
Flow cytometry: 1X10 6 SK-OV-3 cells were intracellularly-stained with PE Rabbit IgG isotype control (A24172,5 µl/Test,left) or PE Rabbit anti-Human CPT1A mAb (A27106,5 µl/Test,right).
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