Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation:
PE
Alternative Synonym:
Cd11a, LFA-1, Ly-15, Ly-21, (p180), LFA-1A
Predicted to enable ICAM-3 receptor activity and cell adhesion molecule binding activity. Involved in cell-cell adhesion. Acts upstream of or within several processes, including activated T cell proliferation, positive regulation of T cell proliferation, and positive regulation of calcium-mediated signaling. Located in cell-cell junction, external side of plasma membrane, and immunological synapse. Is expressed in heart, hemolymphoid system, and vault of skull. Orthologous to human ITGAL (integrin subunit alpha L).
Cross-Reactivity: Mouse. ResearchArea: Signal Transduction Cytoskeleton / ECM Cell Adhesion Integrins AlphaImmunology Cell Type Markers CD AdhesionStem Cells Hematopoietic Progenitors Lymphoid T Lymphocytic LineageStem Cells Hematopoietic Progenitors Lymphoid NK Cell LineageStem Cells Hematopoietic Progenitors Myeloid Monocytic LineageStem Cells Hematopoietic Progenitors Myeloid Neutrophil LineageStem Cells Hematopoietic Progenitors Myeloid Mast Cell LineageStem Cells Hematopoietic Progenitors Myeloid Erythrocytic Lineage. Shipping: Ice Bag
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with PE Rabbit IgG isotype control (A24172,5 µl/Test,left) or PE Rabbit anti-Mouse CD11a mAb (A27336,5 µl/Test,right).
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