Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation:
Biotin
Alternative Synonym:
CD25, Il2r, Ly-43
Enables interleukin-2 binding activity and interleukin-2 receptor activity. Acts upstream of or within several processes, including Notch signaling pathway, activation-induced cell death of T cells, and regulation of T cell proliferation. Located in external side of plasma membrane. Is expressed in bone marrow. Used to study Sjogrens syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in immunodeficiency 41, lymphopenia, multiple sclerosis, type 1 diabetes mellitus, and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha).
Cross-Reactivity: Mouse. ResearchArea: Immunology,Adaptive Immunity,T Cells,CD. Shipping: Ice Bag
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo488 Rabbit anti-Mouse CD4 mAb (A24907,5 µl/Test) and Biotin Rabbit IgG isotype control (5 µl/Test,left) or Biotin Rabbit anti-Mouse CD25 mAb (A27356,0.5 µg,right), followed by PE Streptavidin staining.
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