Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation:
APC
Alternative Synonym:
I-19, ADPRC 1, Cd38-rs1
This gene encodes a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Knockout mice deficient for this gene display altered humoral immune responses. In addition, knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors.
Cross-Reactivity: Mouse. ResearchArea: Immunology,Adaptive Immunity,B Cells,CD. Shipping: Ice Bag
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with APC Rabbit IgG isotype control (A24173,5 µl/Test,left) or APC Rabbit anti-Mouse CD38 mAb (A27365,0.125 µg,right).
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