Biotin Rat anti-Mouse CD3 mAb, Monoclonal

Produktübersicht

• Artikelname: Biotin Rat anti-Mouse CD3 mAb, Monoclonal
• Artikelnummer: ABB-A27842
• Hersteller Artikelnummer: A27842
• Alternativnummer: ABB-A27842-50UG,ABB-A27842-100UG,ABB-A27842-5X100UG
• Hersteller: ABclonal
• Wirt: Rat
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Mouse
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Biotin
• Alternative Synonym: T3d, CD3, T3e, CD3epsilon

Produktbeschreibung

Predicted to enable identical protein binding activity and transmembrane signaling receptor activity. Involved in positive thymic T cell selection. Part of alpha-beta T cell receptor complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in immunodeficiency 19 and severe combined immunodeficiency. Orthologous to human CD3D (CD3d molecule). Predicted to enable several functions, including SH3 domain binding activity, identical protein binding activity, and protein heterodimerization activity. Involved in nervous system development and positive regulation of cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell activation, positive regulation of cytokine production, and regulation of signal transduction. Located in several cellular components, including dendritic spine, external side of plasma membrane, and immunological synapse. Part of alpha-beta T cell receptor complex. Is expressed in colon and hemolymphoid system. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3E (CD3e molecule).

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: FC
• Molekulargewicht: 19kDa/21kDa
• NCBI: 12500
• UniProt: P04235
• Reinheit: Affinity purification
• Target-Kategorie: CD3E/CD3D

Anwendungsbeschreibung

• Application Verdünnung: FC,0.5 µg per million cells in 100 µl volume
• Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Immunology Adaptive Immunity T Cells CDStem Cells Hematopoietic Progenitors Hematopoietic Stem Cells Human Lineage NegativeImmunology Adaptive Immunity Regulatory T Cells. Shipping: Ice Bag

Bilder

Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with Biotin Rat IgG2b isotype control (5 µl/Test,left) or Biotin Rat anti-Mouse CD3 mAb (A27842,0.5 µg,right), followed by ABflo 488 Streptavidin staining.