Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation:
PE
Alternative Synonym:
CD127, IL-7Ralpha
Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R), the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules.
Flow cytometry:1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 488 Rat anti-Mouse CD3 mAb (A27161,5 µl/Test) and PE Rabbit IgG isotype control (A24172,5 µl/Test,left) or PE Rabbit anti-Mouse CD127/IL-7Ralpha mAb (A27862,0.5 µg,right).
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