APC/Cyanine7 Rat anti-Mouse CD45R/B220 mAb, APC/Cy7, Monoclonal

Produktübersicht

• Artikelname: APC/Cyanine7 Rat anti-Mouse CD45R/B220 mAb, APC/Cy7, Monoclonal
• Artikelnummer: ABB-A27988
• Hersteller Artikelnummer: A27988
• Alternativnummer: ABB-A27988-25UG,ABB-A27988-100UG
• Hersteller: ABclonal
• Wirt: Rat
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: APC/Cy7
• Alternative Synonym: loc, B220, Cd45, L-CA, Ly-5, T200, CD45R, Lyt-4

Produktbeschreibung

Enables several functions, including heparan sulfate proteoglycan binding activity, heparin binding activity, and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation, positive regulation of macromolecule metabolic process, and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation, positive regulation of lymphocyte activation, and regulation of protein phosphorylation. Located in external side of plasma membrane, focal adhesion, and membrane raft. Is expressed in several structures, including 3rd branchial arch, alimentary system, cardiovascular system, hemolymphoid system, and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C, multiple sclerosis, severe combined immunodeficiency, and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: FC
• Molekulargewicht: 130kDa/140kDa/144kDa
• NCBI: 19264
• UniProt: P06800
• Reinheit: Affinity purification
• Target-Kategorie: PTPRC

Anwendungsbeschreibung

• Application Verdünnung: FC,0.125 µg per million cells in 100 µl volume
• Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Immunology,Adaptive Immunity,B Cells,CD. Shipping: Ice Bag

Bilder

Flow cytometry:1X10 6 C57BL/6 mouse splenocytes were surface-stained with ABflo 450 Rabbit anti-Mouse CD19 mAb (A26192,5 µl/Test) and APC/Cyanine7 Rat IgG2a isotype control (5 µl/Test,left) or APC/Cyanine7 Rat anti-Mouse CD45R/B220 mAb (A27988,0.125 µg,right).