Biotin Rabbit anti-Mouse CD49b/ITGA2 mAb, Monoclonal

Produktübersicht

• Artikelname: Biotin Rabbit anti-Mouse CD49b/ITGA2 mAb, Monoclonal
• Artikelnummer: ABB-A28151
• Hersteller Artikelnummer: A28151
• Alternativnummer: ABB-A28151-5X100UG,ABB-A28151-50UG,ABB-A28151-100UG
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: Biotin
• Alternative Synonym: DX5, GPIa, CD49B

Produktbeschreibung

Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway, positive regulation of cell migration, and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system, brain, cardiovascular system, eye, and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcets disease, artery disease (multiple), blood platelet disease (multiple), diabetes mellitus (multiple), and von Willebrands disease (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2).

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: FC
• Molekulargewicht: 129 kDa
• NCBI: 16398
• UniProt: Q62469
• Reinheit: Affinity purification
• Target-Kategorie: Itga2

Anwendungsbeschreibung

• Application Verdünnung: FC,0.5 µg per million cells in 100 µl volume
• Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Immunology Adaptive Immunity T Cells CDSignal Transduction Cytoskeleton / ECM Cell Adhesion Integrins Alpha. Shipping: Ice Bag

Bilder

Flow cytometry: 1X106 C57BL/6 mouse splenocytes were surface-stained with APC Rabbit anti-Mouse CD161c/NK1.1 mAb (A25913,5 µl/Test) and Biotin Rabbit IgG isotype control (A25626,5 µl/Test,left) or Biotin Rabbit anti-Mouse Integrin alpha 2/CD49b mAb (A28151,0.5 µg,right), followed by ABflo 488 Streptavidin staining.