Biotin Rat anti-Mouse CD45R/B220 mAb, Monoclonal

Artikelnummer: ABB-A28202
Artikelname: Biotin Rat anti-Mouse CD45R/B220 mAb, Monoclonal
Artikelnummer: ABB-A28202
Hersteller Artikelnummer: A28202
Alternativnummer: ABB-A28202-100UG,ABB-A28202-5X100UG
Hersteller: ABclonal
Wirt: Rat
Kategorie: Antikörper
Applikation: FC
Spezies Reaktivität: Mouse
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: Biotin
Alternative Synonym: loc, B220, Cd45, L-CA, Ly-5, T200, CD45R, Lyt-4
Enables several functions, including heparan sulfate proteoglycan binding activity, heparin binding activity, and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation, positive regulation of macromolecule metabolic process, and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation, positive regulation of lymphocyte activation, and regulation of protein phosphorylation. Located in external side of plasma membrane, focal adhesion, and membrane raft. Is expressed in several structures, including 3rd branchial arch, alimentary system, cardiovascular system, hemolymphoid system, and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C, multiple sclerosis, severe combined immunodeficiency, and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).
Klonalität: Monoclonal
Konzentration: FC
Molekulargewicht: 130kDa/140kDa/144kDa
NCBI: 19264
UniProt: P06800
Reinheit: Affinity purification
Target-Kategorie: PTPRC
Application Verdünnung: FC,0.25 µg per million cells in 100 µl volume
Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Immunology,Adaptive Immunity,B Cells,CD. Shipping: Ice Bag
Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes were surface-stained with Biotin Rat IgG2a isotype control (5 µl/Test,left) or Biotin Rat anti-Mouse CD45R/B220 mAb (A28202,0.25 µg,right), followed by ABflo 488 Streptavidin staining.