Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and adaptive immune response. Located in external side of plasma membrane. Is expressed in several structures, including cardiovascular system, central nervous system, genitourinary system, hemolymphoid system, and intestine. Orthologous to human ADGRE1 (adhesion G protein-coupled receptor E1).
Flow cytometry: 1X10 6 C57BL/6 mouse bone marrow cells were surface-stained with ABflo 450 Rabbit anti-Mouse CD11b mAb (A26229,5 µl/Test) and ABflo 488 Rabbit IgG isotype control (A22069,5 µl/Test,left) or ABflo 488 Rabbit anti-Mouse F4/80 mAb (A28286,0.25 µg,right).
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