NLRP6 Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: NLRP6 Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A28419
• Hersteller Artikelnummer: A28419
• Alternativnummer: ABB-A28419-500UL,ABB-A28419-100UL,ABB-A28419-20UL,ABB-A28419-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: AVR, NAVR, PAN3, NALP6, PYPAF5, CLR11.4, NAVR/AVR

Produktbeschreibung

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 99 kDa
• NCBI: 171389
• UniProt: P59044
• Reinheit: Affinity purification
• Target-Kategorie: NLRP6

Anwendungsbeschreibung

• Application Verdünnung: WB,1:3000 - 1:10000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.For high-ratio antibody dilutions (1:10000),a sequential dilution method is strongly recommended to ensure
• Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Apoptosis,Caspases,Immunology Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway. Shipping: Ice Bag

Bilder

Western blot analysis of lysates from SW1463 cells using NLRP6 Rabbit mAb (A28419) at 1:5000 dilution incubated overnight at 4°C.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45 s.