PE/Cyanine7 Rabbit anti-Mouse CD223/LAG-3 mAb, PE/Cy7, Monoclonal

Produktübersicht

• Artikelname: PE/Cyanine7 Rabbit anti-Mouse CD223/LAG-3 mAb, PE/Cy7, Monoclonal
• Artikelnummer: ABB-A28466
• Hersteller Artikelnummer: A28466
• Alternativnummer: ABB-A28466-100UG,ABB-A28466-25UG
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC
• Spezies Reaktivität: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: PE/Cy7
• Alternative Synonym: Ly66, CD223, LAG-3

Produktbeschreibung

Enables MHC class II protein binding activity and transmembrane signaling receptor activity. Involved in negative regulation of regulatory T cell differentiation, plasmacytoid dendritic cell activation, and regulation of immune response. Acts upstream of or within cell surface receptor signaling pathway, negative regulation of interleukin-2 production, and positive regulation of natural killer cell mediated cytotoxicity. Located in external side of plasma membrane and extracellular region. Orthologous to human LAG3 (lymphocyte activating 3).

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: FC
• Molekulargewicht: 57 kDa
• NCBI: 16768
• UniProt: Q61790
• Reinheit: Affinity purification
• Target-Kategorie: LAG-3

Anwendungsbeschreibung

• Application Verdünnung: FC,0.25 µg per million cells in 100 µl volume
• Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Immunology Inflammation,CDs. Shipping: Ice Bag

Bilder

Flow cytometry: 1X10 6 C57BL/6 mouse splenocytes (untreated,left) and C57BL/6 mouse splenocytes treated with 2ug/ml Mouse T Cell Activation Kit (Anti-CD3/CD28) for 3days (right) were surface-stained with ABflo 488 Rat anti-Mouse CD3 mAb (A27161,5 µl/Test) and PE/Cyanine7 Rabbit anti-Mouse CD223/LAG-3 mAb (A28466,0.25 µg).