MIB1/DIP1 Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: MIB1/DIP1 Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A3371
• Hersteller Artikelnummer: A3371
• Alternativnummer: ABB-A3371-100UL,ABB-A3371-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2, MIB1/DIP1

Produktbeschreibung

This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 110kDa
• NCBI: 57534
• UniProt: Q86YT6
• Reinheit: Affinity purification
• Target-Kategorie: MIB1

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction,Cell Biology Developmental Biology,Stem Cells. Shipping: Ice Bag

Bilder

Western blot analysis of various lysates using MIB1/DIP1 Rabbit mAb (A3371) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3min.