TRIB3 Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: TRIB3 Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A3523
• Hersteller Artikelnummer: A3523
• Alternativnummer: ABB-A3523-100UL,ABB-A3523-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: NIPK, SINK, TRB3, SKIP3, C20orf97, TRIB3

Produktbeschreibung

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 40kDa
• NCBI: 57761
• UniProt: Q96RU7
• Reinheit: Affinity purification
• Target-Kategorie: TRIB3

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Signal Transduction,Kinase,Cell Biology Developmental Biology,Apoptosis,Cell Cycle,Cell differentiation,Endocrine Metabolism,Endocrine and metabolic diseases,Diabetes,Cardiovascular. Shipping: Ice Bag

Bilder

Western blot analysis of lysates from K-562 cells, using TRIB3 Rabbit mAb (A3523) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.