GUCY2D Rabbit pAb, Unconjugated, Polyclonal

Produktübersicht

• Artikelname: GUCY2D Rabbit pAb, Unconjugated, Polyclonal
• Artikelnummer: ABB-A3605
• Hersteller Artikelnummer: A3605
• Alternativnummer: ABB-A3605-20UL,ABB-A3605-100UL,ABB-A3605-500UL,ABB-A3605-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: LCA, CACD, CG-E, CYGD, LCA1, RCD2, CACD1, CORD5, CORD6, GUC2D, ROSGC, retGC, CSNB1I, GUC1A4, RETGC-1, ROS-GC1, GUCY2D

Produktbeschreibung

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 120kDa
• NCBI: 3000
• UniProt: Q02846
• Reinheit: Affinity purification
• Sequenz: AVFTVGVLGPWACDPIFSRARPDLAARLAAARLNRDPGLAGGPRFEVALLPEPCRTPGSLGAVSSALARVSGLVGPVNPAACRPAELLAEEAGIALVPWGCPWTQAEGTTAPAVTPAADALYALLRAFGWARVALVTAPQDLWVEAGRSLSTALRARGLPVASVTSMEPLDLSGAREALRKVRDGPRVTAVIMVMHSVLLGGEEQRYLLEAAEELGLTDGSLVFLPFDTIHYALSPGPEALAALANSSQLRRAHD
• Target-Kategorie: GUCY2D
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:200 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction,Neuroscience. Shipping: Ice Bag

Bilder

Western blot analysis of various lysates using GUCY2D Rabbit pAb (A3605) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.