MXD1 Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer:
ABB-A3613
- Bilder (1)
| Artikelname: | MXD1 Rabbit pAb, Unconjugated, Polyclonal |
| Artikelnummer: | ABB-A3613 |
| Hersteller Artikelnummer: | A3613 |
| Alternativnummer: | ABB-A3613-20UL,ABB-A3613-100UL,ABB-A3613-1000UL,ABB-A3613-500UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | MAD, MAD1, BHLHC58, MXD1 |
| This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Application Verdünnung: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human,Rat. ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway. Shipping: Ice Bag |
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Western blot analysis of various lysates using MXD1 Rabbit pAb (A3613) at 1:800 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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