Caspr1 Rabbit mAb, Unconjugated, Monoclonal

Produktübersicht

• Artikelname: Caspr1 Rabbit mAb, Unconjugated, Monoclonal
• Artikelnummer: ABB-A3721
• Hersteller Artikelnummer: A3721
• Alternativnummer: ABB-A3721-100UL,ABB-A3721-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: CHN3, P190, CASPR, NRXN4, CNTNAP, Caspr1

Produktbeschreibung

The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for contactin-associated protein, includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 156kDa
• NCBI: 8506
• UniProt: P78357
• Reinheit: Affinity purification
• Target-Kategorie: CNTNAP1

Anwendungsbeschreibung

• Application Verdünnung: WB,1:1000 - 1:4000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human. ResearchArea: Neuroscience, Cell Type Marker. Shipping: Ice Bag

Bilder

Western blot analysis of lysates from U-87MG cells, using Caspr1 (A3721) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 3s.