CHM Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer:
ABB-A8345
- Bilder (1)
| Artikelname: | CHM Rabbit pAb, Unconjugated, Polyclonal |
| Artikelnummer: | ABB-A8345 |
| Hersteller Artikelnummer: | A8345 |
| Alternativnummer: | ABB-A8345-20UL,ABB-A8345-100UL,ABB-A8345-500UL,ABB-A8345-1000UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | TCD, GGTA, REP-1, DXS540, HSD-32, CHM |
| This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. |
| Application Verdünnung: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human. ResearchArea: Signal Transduction,Neuroscience. Shipping: Ice Bag |
|
|
Western blot analysis of various lysates using CHM Rabbit pAb (A8345) at 1:1000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25µg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 5s. |
Produktgarantie und fachkundiger Support
