ATP7A Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: ATP7A Rabbit pAb, Unconjugated
• Artikelnummer: ABB-A8399
• Hersteller Artikelnummer: A8399
• Alternativnummer: ABB-A8399-100UL, ABB-A8399-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: MK, MNK, DSMAX, SMAX3, ATP7A

Produktbeschreibung

This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.

Produkteigenschaften

• Molekulargewicht: 11-172 kDa
• NCBI: 538
• UniProt: Q04656
• Reinheit: Affinity purification
• Target-Kategorie: ATP7A

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Rat, ResearchArea: Cancer,Signal Transduction,Endocrine Metabolism,Neuroscience,Neurodegenerative Diseases.

Bilder

Western blot analysis of lysates from Rat lung usingATP7A Rabbit pAb (A8399) at1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.