PTPRU Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: PTPRU Rabbit pAb, Unconjugated
• Artikelnummer: ABB-A8475
• Hersteller Artikelnummer: A8475
• Alternativnummer: ABB-A8475-100UL,ABB-A8475-20UL,ABB-A8475-1000UL,ABB-A8475-500UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: FMI, PTP, PCP-2, PTP-J, PTPRO, PTPU2, PTP-PI, PTP-RO, PTPPSI, hPTP-J, R-PTP-U, R-PTP-PSI, PTPRU

Produktbeschreibung

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 162kDa
• NCBI: 10076
• UniProt: Q92729
• Reinheit: Affinity purification
• Sequenz: MARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCV
• Target-Kategorie: PTPRU
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Mouse,Rat, ResearchArea: Signal Transduction.

Bilder

Western blot analysis of lysates from Mouse brain , using PTPRU Rabbit pAb (A8475) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.