Phospho-MEF2C-S396 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-MEF2C-S396 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0075
• Hersteller Artikelnummer: AP0075
• Alternativnummer: ABB-AP0075-20UL,ABB-AP0075-500UL,ABB-AP0075-1000UL,ABB-AP0075-100UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: NEDHSIL, DEL5q14.3, C5DELq14.3, Phospho-MEF2C-S396

Produktbeschreibung

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 51kDa
• NCBI: 4208
• UniProt: Q06413
• Reinheit: Affinity purification
• Sequenz: PVSPP
• Target-Kategorie: MEF2C
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Epigenetics Nuclear Signaling,Transcription Factors,Protein phosphorylation,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology Developmental Biology,Endocrine Metabolism,AMPK Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Heart,Cardiogenesis,Hypertrophy.

Bilder

Western blot analysis of lysates from K-562 and MCF-7 cells, using Phospho-MEF2C-S396 Rabbit pAb (AP0075) at 1:1000 dilution. K562 cells were treated by 10% FBS for 30 minutes after serum-starvation overnight. MCF7 cells were treated by EGF (100ng/mL) for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.