Phospho-GluR1/GRIA1-S849 Rabbit pAb, Unconjugated

Artikelnummer: ABB-AP0242
Artikelname: Phospho-GluR1/GRIA1-S849 Rabbit pAb, Unconjugated
Artikelnummer: ABB-AP0242
Hersteller Artikelnummer: AP0242
Alternativnummer: ABB-AP0242-100UL, ABB-AP0242-20UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: GLUH1, GLUR1, GLURA, GluA1, HBGR1, MRD67, MRT76, Phospho-GluR1/GRIA1-S849
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Molekulargewicht: 102kDa
NCBI: 2890
UniProt: P42261
Reinheit: Affinity purification
Target-Kategorie: GRIA1
Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Protein phosphorylation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Dopamine Signaling in Parkinsons Disease.
Western blot analysis of lysates from rat brain tissue using Phospho-GluR1/GRIA1-S849 Rabbit pAb (AP0242).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.