Phospho-MEK6-S207 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-MEK6-S207 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0393
• Hersteller Artikelnummer: AP0393
• Alternativnummer: ABB-AP0393-100UL, ABB-AP0393-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, SAPKK-3, Phospho-MEK6-S207

Produktbeschreibung

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Produkteigenschaften

• Molekulargewicht: 37kDa
• NCBI: 5608
• UniProt: P52564
• Reinheit: Affinity purification
• Target-Kategorie: MAP2K6

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200
• Anwendungsbeschreibung: Cross-Reactivity: Human,Rat, ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Cell Biology Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cytoskeleton,Actins,TGF-b-Smad Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,Jak-Stat-IL-6 Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Neuroscience,Neurodegenerative Diseases.

Bilder

Western blot analysis of lysates from HL60 cells, using Phospho-MEK6-S207 Rabbit pAb (AP0393).
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.