Phospho-Syk-Y352/ZAP70-Y319 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-Syk-Y352/ZAP70-Y319 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0501
• Hersteller Artikelnummer: AP0501
• Alternativnummer: ABB-AP0501-100UL, ABB-AP0501-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: SYK/ZAP70, Phospho-Syk-Y352/ZAP70-Y319

Produktbeschreibung

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Produkteigenschaften

• Molekulargewicht: 69kDa/72kDa/35kDa/55kDa
• NCBI: 6850
• UniProt: P43405
• Reinheit: Affinity purification
• Target-Kategorie: SYK/ZAP70

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Protein phosphorylation.

Bilder

Western blot analysis of lysates from Jurkat cells, using Phospho-Syk-Y352/ZAP70-Y319 Rabbit pAb (AP0501) at 1:1000 dilution. Jurkat cells were treated with 10% FBS for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.