Phospho-PDGFR alpha-Y849 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-PDGFR alpha-Y849 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0569
• Hersteller Artikelnummer: AP0569
• Alternativnummer: ABB-AP0569-20UL,ABB-AP0569-100UL,ABB-AP0569-500UL,ABB-AP0569-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: CD140A, PDGFR2, PDGFR-2, Phospho-PDGFR alpha-Y849

Produktbeschreibung

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 123kDa
• NCBI: 5156
• UniProt: P16234
• Reinheit: Affinity purification
• Sequenz: SNYVS
• Target-Kategorie: PDGFRA
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology Developmental Biology,Growth factors,Immunology Inflammation,CDs,Cardiovascular,Angiogenesis.

Bilder

Western blot analysis of lysates from HepG2 cells, using Phospho-PDGFR alpha-Y849 Rabbit pAb (AP0569) at 1:1000 dilution. HepG2 cells were treated with EGF (100ng/mL) for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.