Phospho-STK11-S334 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-STK11-S334 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0601
• Hersteller Artikelnummer: AP0601
• Alternativnummer: ABB-AP0601-20UL,ABB-AP0601-1000UL,ABB-AP0601-500UL,ABB-AP0601-100UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: PJS, LKB1, hLKB1, Phospho-STK11-S334

Produktbeschreibung

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 49kDa
• NCBI: 6794
• UniProt: Q15831
• Reinheit: Affinity purification
• Sequenz: WRSMT
• Target-Kategorie: STK11
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Protein phosphorylation,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Serine threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect.

Bilder

Western blot analysis of lysates from HeLa cells, using Phospho-STK11-S334 Rabbit pAb (AP0601) at 1:1000 dilution. Hela cells were treated with UV at room temperature for 30 minutes and PMA (200 nM) at 37°C for 30 minutes after serum-starvation
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.