Phospho-PKC delta-T505 Rabbit pAb, Unconjugated

Artikelnummer: ABB-AP0776
Artikelname: Phospho-PKC delta-T505 Rabbit pAb, Unconjugated
Artikelnummer: ABB-AP0776
Hersteller Artikelnummer: AP0776
Alternativnummer: ABB-AP0776-20UL,ABB-AP0776-100UL,ABB-AP0776-500UL,ABB-AP0776-1000UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: MAY1, PKCD, ALPS3, CVID9, nPKC-delta, Phospho-PKC delta-T505
The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome.
Klonalität: Polyclonal
Molekulargewicht: 78kDa
NCBI: 5580
UniProt: Q05655
Reinheit: Affinity purification
Sequenz: SRAST
Target-Kategorie: PRKCD
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,Kinase,Serine threonine kinases,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,TGF-b-Smad Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,Neuroscience.
Western blot analysis of lysates from U-937 cells, using Phospho-PKC delta-T505 Rabbit pAb (AP0776) at 1:2000 dilution. U-937 cells were treated with PMA/TPA (200nM) for 30 minutes.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.