Phospho-MYH9-S1943 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-MYH9-S1943 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0802
• Hersteller Artikelnummer: AP0802
• Alternativnummer: ABB-AP0802-100UL, ABB-AP0802-20UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: MHA, FTNS, EPSTS, BDPLT6, DFNA17, MATINS, NMMHCA, NMHC-II-A, NMMHC-IIA, Phospho-MYH9-S1943

Produktbeschreibung

This gene encodes a conventional non-muscle myosin, this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Produkteigenschaften

• Molekulargewicht: 227kDa
• NCBI: 4627
• UniProt: P35579
• Reinheit: Affinity purification
• Target-Kategorie: MYH9

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Protein phosphorylation,Signal Transduction,Cell Biology Developmental Biology,Cytoskeleton,Motor Proteins.

Bilder

Western blot analysis of lysates from 293T cells, using Phospho-MYH9-S1943 Rabbit pAb (AP0802) at 1:2000 dilution. 293T cell lysates were treated by CIP at 37C for 1 hour.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 30s.