Phospho-CRMP2/DPYSL2-T514 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-CRMP2/DPYSL2-T514 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0821
• Hersteller Artikelnummer: AP0821
• Alternativnummer: ABB-AP0821-20UL,ABB-AP0821-100UL,ABB-AP0821-1000UL,ABB-AP0821-500UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: DRP2, N2A3, CRMP2, DRP-2, ULIP2, CRMP-2, DHPRP2, ULIP-2, Phospho-CRMP2/DPYSL2-T514

Produktbeschreibung

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimers disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 62kDa
• NCBI: 1808
• UniProt: Q16555
• Reinheit: Affinity purification
• Sequenz: TVTPA
• Target-Kategorie: DPYSL2
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Protein phosphorylation,Cell Biology Developmental Biology,Microtubules,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease.

Bilder

Western blot analysis of various lysates using Phospho-CRMP2/DPYSL2-T514 Rabbit pAb (AP0821) at 1:1000 dilution or CRMP2/DPYSL2 antibody (A14570). SH-SY5Y cells were treated by CIP(20uL/400ul) at 37°C for 1 hour. PC-12 cells were treated by CIP(20uL/400ul) at 37°C for 1 hour.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.