Phospho-PKC delta-S645 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-PKC delta-S645 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP0972
• Hersteller Artikelnummer: AP0972
• Alternativnummer: ABB-AP0972-20UL,ABB-AP0972-100UL,ABB-AP0972-1000UL,ABB-AP0972-500UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: MAY1, PKCD, ALPS3, CVID9, nPKC-delta, Phospho-PKC delta-S645

Produktbeschreibung

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 78kDa
• NCBI: 5580
• UniProt: Q05655
• Reinheit: Affinity purification
• Sequenz: RLSYS
• Target-Kategorie: PRKCD
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,Kinase,Serine threonine kinases,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,TGF-b-Smad Signaling Pathway,Immunology Inflammation,B Cell Receptor Signaling Pathway,Neuroscience.

Bilder

Western blot analysis of lysates from 293T cells, using Phospho-PKC delta-S645 pAb (AP0972) at 1:1000 dilution or PKC delta antibody (A0471). 293T cells were treated with PMA/TPA (200 nM) at 37°C for 30 minutes after serum-starvation overnight.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.