Phospho-DDR1-Y792 Rabbit pAb

Produktübersicht

• Artikelname: Phospho-DDR1-Y792 Rabbit pAb
• Artikelnummer: ABB-AP1072
• Hersteller Artikelnummer: AP1072
• Alternativnummer: ABB-AP1072-100UL,ABB-AP1072-20UL,ABB-AP1072-500UL,ABB-AP1072-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Alternative Synonym: CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, CD167, EDDR1, MCK10, NTRK4, PTK3A, Phospho-DDR1-Y792

Produktbeschreibung

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 101kDa
• NCBI: 780
• UniProt: Q08345
• Reinheit: Affinity purification
• Sequenz: NLYAG
• Target-Kategorie: DDR1
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Immunology Inflammation,CDs,Neuroscience,Cardiovascular,Heart,Cardiogenesis.

Bilder

Western blot analysis of various lysates using Phospho-DDR1-Y792 Rabbit pAb (AP1072) at 1:1000 dilution. 293T cells were treated with ATP(5 mM) at 30°C for 1 hour. NIH/3T3 cells were treated with ATP(5 mM) at 30°C for 1 hour. C6 cells were treated with ATP(5 mM) at 30°C for 1 hour.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% BSA.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.