Phospho-Tau-T181 Rabbit pAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-Tau-T181 Rabbit pAb, Unconjugated
• Artikelnummer: ABB-AP1234
• Hersteller Artikelnummer: AP1234
• Alternativnummer: ABB-AP1234-100UL,ABB-AP1234-20UL,ABB-AP1234-1000UL,ABB-AP1234-500UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, tau-40, FTDP-17, PPP1R103, Tau-PHF6, Phospho-Tau-T181

Produktbeschreibung

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 32-45kDa/78- 80kDa
• NCBI: 4137
• UniProt: P10636
• Reinheit: Affinity purification
• Sequenz: PKTPP
• Target-Kategorie: MAPT
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse, ResearchArea: Protein phosphorylation,Signal Transduction,Cell Biology Developmental Biology,Apoptosis,Cytoskeleton,Microtubules,Neuroscience, Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Stem Cells,Neuron marker.

Bilder

Western blot analysis of various lysates, using Phospho-Tau-T181 Rabbit pAb (AP1234) at 1:600 dilution. Mouse brain cells were treated by lambda-PP mixed solution (1ul) at 30°C for 30 minutes.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 30s.