Phospho-Camk2-T286 Rabbit mAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-Camk2-T286 Rabbit mAb, Unconjugated
• Artikelnummer: ABB-AP1386
• Hersteller Artikelnummer: AP1386
• Alternativnummer: ABB-AP1386-100UL,ABB-AP1386-20UL,ABB-AP1386-500UL,ABB-AP1386-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: CAMKA, MRD53, MRT63, CaMKIIalpha, CaMKIINalpha, CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta, CAMKD, CAMK, CAMKG, MRD59, CAMK-II, Phospho-Camk2-T286

Produktbeschreibung

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2 )/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [ARC57709]
• Molekulargewicht: 54 kDa
• NCBI: 816
• UniProt: Q13554
• Reinheit: Affinity purification
• Sequenz: QETVD
• Target-Kategorie: CAMK2
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Mouse, ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,Kinase,Serine threonine kinases,ErbB-HER Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Microtubules,Endocrine Metabolism,Carbohydrate metabolism,Immunology Inflammation,B Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Cardiovascular,Heart,Hypertrophy.

Bilder

Western blot analysis of lysates from Mouse brain using Phospho-Camk2-T286 Rabbit mAb (AP1386) at 1:1000 dilutionincubated at room temperature for 1.5 hours. Mouse brain treated with CIP (1U/ul) at 37°C for 1 hours.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 30 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 45 s.