Phospho-p90Rsk/RSK1/RPS6KA1-T348 Rabbit pAb

Produktübersicht

• Artikelname: Phospho-p90Rsk/RSK1/RPS6KA1-T348 Rabbit pAb
• Artikelnummer: ABB-AP1397
• Hersteller Artikelnummer: AP1397
• Alternativnummer: ABB-AP1397-20UL,ABB-AP1397-100UL,ABB-AP1397-500UL,ABB-AP1397-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Alternative Synonym: RSK, HU-1, RSK1, p90Rsk, MAPKAPK1, MAPKAPK1A, Phospho-p90Rsk/RSK1/RPS6KA1-T348

Produktbeschreibung

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: 83kDa
• NCBI: 6195
• UniProt: Q15418
• Reinheit: Affinity purification
• Target-Kategorie: RPS6KA1
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat, ResearchArea: Epigenetics Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Protein phosphorylation,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors Signaling to MAPK Erk,Kinase,Serine threonine kinases,mTOR Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,Cell Cycle Control-G2 M DNA Damage Checkpoint,Microtubules,Immunology Inflammation,NF-kB Signaling Pathway,Neuroscience.

Bilder

Western blot analysis of lysates from HeLa cells, using Phospho-p90Rsk/RSK1/RPS6KA1-T348 Rabbit pAb (AP1397) at 1:600 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.