Phospho-Axl-Y702 Rabbit mAb, Unconjugated

Produktübersicht

• Artikelname: Phospho-Axl-Y702 Rabbit mAb, Unconjugated
• Artikelnummer: ABB-AP1427
• Hersteller Artikelnummer: AP1427
• Alternativnummer: ABB-AP1427-100UL,ABB-AP1427-20UL,ABB-AP1427-500UL,ABB-AP1427-1000UL
• Hersteller: ABclonal
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Spezies Reaktivität: Human
• Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
• Konjugation: Unconjugated
• Alternative Synonym: ARK, UFO, JTK11, Tyro7, Phospho-Axl-Y702

Produktbeschreibung

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [ARC58385]
• Molekulargewicht: 98 kDa
• NCBI: 558
• UniProt: P30530
• Reinheit: Affinity purification
• Target-Kategorie: AXL
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
• Anwendungsbeschreibung: Cross-Reactivity: Human, ResearchArea: Protein phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology Developmental Biology,Cell Cycle,Immunology Inflammation.

Bilder

Western blot analysis of lysates from wild type (WT) and A-549 cells transfected with Gas6 using Phospho-Axl-Y702 Rabbit mAb (AP1427) at 1:500 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit (RM00021).
Exposure time: 180s.