Serum, plasma, cell culture supernatant, and other biological fluids.
Konjugation:
Biotin
Alternative Synonym:
OB, obese
Enables hormone activity and peptide hormone receptor binding activity. Involved in several processes, including positive regulation of cell communication, regulation of apoptotic process, and response to vitamin. Located in cytosol and extracellular space. Used to study several diseases, including alcohol dependence, glucose metabolism disease (multiple), liver disease (multiple), neurodegenerative disease (multiple), and short bowel syndrome. Biomarker of several diseases, including Huntingtons disease, alcohol dependence, fatty liver disease (multiple), lipid metabolism disorder (multiple), and obesity. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence, congenital leptin deficiency, fatty liver disease (multiple), liver disease (multiple), and lung disease (multiple). Orthologous to human LEP (leptin).
