Recombinant Human Complement C1r subcomponent Protein
Artikelnummer:
ABB-RP00142
Hersteller Artikelnummer:
RP00142
Alternativnummer:
ABB-RP00142-50UG, ABB-RP00142-20UG
Hersteller:
ABclonal
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Immunogen:
Met1-Asp705
Alternative Synonym:
C1R,EDSPD1
The classical complement pathway plays a major role in innate immunity against infection. This pathway is triggered by C1, a multimolecular complex composed of the recognition protein C1q and two serine proteases, C1r and C1s. Following the C1q recognition, C1r is autoactivated, and in turn activates C1s, which cleaves C4 and C2, the C1 substrates. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This protien recognizes full-length C1r chain and the cleaved B chain.
Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Target-Kategorie:
Complement C1r subcomponent
Application Verdünnung:
Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Anwendungsbeschreibung:
Cross-Reactivity: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein
Recombinant Human Complement C1r subcomponent Protein was determined by SDS-PAGE under reducing (R) and non-reducing (NR) conditions.
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