Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of This protein is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.
Lyophilized from a 0.2 µm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.
Target-Kategorie:
CCL23/Ck beta 8-1
Application Verdünnung:
Lyophilized from a 0.2 µm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.
Anwendungsbeschreibung:
Cross-Reactivity: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Cytokines & Cytokine Receptors
Recombinant Human CCL23/Ck beta 8-1 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
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